The mean cell hemoglobin or MCH is a calculated red blood cell (RBC) index that gives an indication of the average amount (in pg) of hemoglobin in the red blood cells (RBC). It is calculated from the spectrophotometrically measured hemoglobin concentration (after lysis of RBCs) and RBC count so it represents the amount of hemoglobin per RBC.
Blood Examinations. Laboratory factors including preoperative serum MCV, mean corpuscular hemoglobin (MCH), mean corpuscular hemoglobin concentration (MCHC), red cell distribution width (RDW), and hemoglobin (Hb) were obtained within 7 days before surgery.
Red blood cell count: A normal red blood cell count is 4.32 to 5.72 trillion cells/L in men and 3,90 to 5.03 trillion cells/L in women. Hemoglobin: A hemoglobin level less than 13.5 grams/100 ml in men or 12.0 grams/100 ml in women is considered low. Hematocrit: A normal hematocrit level is 42% to 54% in men and 38% to 46% in women.
As such, if the size of the red blood cells is large (as measured by the MCV), the amount of hemoglobin per red blood cell will be high (as measured by the MCH), and vice versa. A normal reference range for MCH is between 27 and 32 pg/cell.
A high MCHC means that hemoglobin is more concentrated than usual and may occur in a few ways. For instance, hemoglobin becomes more concentrated when red blood cells break down. MCHC is often increased in people who smoke. 10 MCHC may also be falsely increased due to cold agglutinin disease.
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high red blood cell count but low mcv and mch
